For Web sites to be usable for a global audience, those sites must be adapted to many local requirements. This paper examines key issues in such adaptation (termed localization), considers the costs and specific aspects of software that must be localized, and presents an approach for analyzing and documenting software localization. The paper is based on a review of relevant literature, meetings with localization industry representatives, and an ongoing participant observation in a global telehealth company. Examples from the company illustrate the localization issues and their possible outcomes or solutions.